WEBKNOSSOS is a scalable platform for working with large volume EM (electron microscopy) datasets, addressing the growing challenges in data volume and workflow complexity in this field. It supports the full analysis pipeline: visualization, annotation, sharing, and processing of volume EM data, including specialized capabilities like registration and automatic segmentation. In combination with OME-Zarr (a cloud-ready, interoperable data format), WEBKNOSSOS forms part of a framework that enables efficient, collaborative work on large-scale volume EM datasets across distributed teams and tools. Learn more at webknossos.org